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  • Goldenseal is a rich source of berberine and other alkaloids possessing antimicrobial effects, especially against intestinal micro-organisms (Planta Med 2001;67: 561-4; Antibiotics 1976;3:577-88).
  • The gastrointestinal anti-inflammatory, antisecretory and antimicrobial effects of berberine are effective in normalizing intestinal function and transit time (Altern Med Rev 1997;2:94-103).
  • Animal studies have found the specific combination of Echinacea and Goldenseal stimulates the humoral immune system to produce immunoglobulins (Immunol Lett 1999;68:391-5).